The Most Misunderstood Compound! Full SR-9009 Breakdown (Benefits, Side Effects, Dosing, and More!) January 2025

his article friends is designed to go along with the youtube video done on the subject. In this article we will discuss.

What Is SR-9009
How It Works In the Body
Benefits of SR-9009
Side Effects of SR-9009
The Best Route of Administration
SR-9009 vs Cardarine
My Experience with SR-9009
Dosing SR-9009

And more!

Where to Find SR-9009? If You are Looking for SR-9009 Sourcing It Can be Found Below

Modern Aminos Injectable SR-9009 Code: biohack

Amino Asylum Injectable SR-9009 Code: biohack

Amino Asylum Injectable SR-9009 and Cardarine Blend code: biohack

What Is SR-9009

SR-9009, often referred to as Stenabolic, is a synthetic compound initially developed by Dr. Thomas Burris and his research team at The Scripps Research Institute. This innovative compound was not designed as a performance-enhancing drug but as a tool to better understand the role of Rev-ERBα, a critical protein in the body. Over time, its potential applications in improving metabolic health, energy regulation, and more have sparked significant interest, particularly in the fitness and biohacking communities.

How Does It Work In the Body?

SR-9009 is a Rev-ERBα agonist, meaning it binds to and activates the Rev-ERBα protein. Rev-ERBα is part of the body’s circadian rhythm and metabolic regulation system. This compound was initially developed to explore treatments for metabolic diseases, obesity, and related conditions. While it has shown promise in preclinical research, SR-9009 has not yet been approved for human use, and much of the evidence surrounding its effects comes from animal studies or anecdotal reports.

What Is the Rev-Erb?

The Rev-ERB system, primarily composed of Rev-ERBα and Rev-ERBβ proteins, plays a pivotal role in regulating the circadian rhythm, metabolism, and inflammatory responses. These proteins act as transcriptional repressors, influencing the expression of genes involved in energy production, lipid and glucose metabolism, and mitochondrial function.

By activating Rev-ERBα, SR-9009 enhances the body’s ability to regulate energy expenditure, mitochondrial activity, and fat metabolism. It essentially prompts the body to operate in a more metabolically efficient state, similar to the effects of physical exercise. Key functions of the Rev-ERB system include:

Circadian Rhythm Regulation: Influencing the body’s internal clock and aligning biological processes with day-night cycles.
Metabolic Regulation: Controlling the storage and breakdown of fat and glucose.
Inflammation Modulation: Suppressing pro-inflammatory pathways.

SR-9009 Benefits

SR-9009 has demonstrated a wide range of potential benefits, particularly in areas related to metabolism, energy, and health optimization. While many findings are based on preclinical studies, the compound’s effects make it an appealing tool for biohackers and researchers.

1. Improved Sleep

As a modulator of the circadian rhythm, SR-9009 can promote better alignment of the sleep-wake cycle. By enhancing Rev-ERB activity, it helps regulate sleep patterns, potentially benefiting those with disrupted circadian rhythms or insomnia.

2. Enhanced Energy and Endurance

SR-9009 increases mitochondrial biogenesis, resulting in more efficient energy production. This makes it highly appealing to athletes and individuals looking to boost stamina and endurance. In animal studies, SR-9009 improved exercise capacity significantly, leading to its nickname as “exercise in a pill.”

3. Support for Metabolic Health

SR-9009 can enhance glucose and lipid metabolism, potentially reducing the risk of obesity and type 2 diabetes. By promoting fat oxidation and reducing the storage of excess lipids, it helps create a healthier metabolic profile.

4. Reduction in Inflammation

Through the suppression of inflammatory pathways, SR-9009 may offer benefits for conditions linked to chronic inflammation, such as autoimmune disorders and metabolic syndromes.

5. Potential Aid in Fat Loss

By stimulating Rev-ERBα, SR-9009 enhances the breakdown of stored fats and reduces the generation of new fat cells. This makes it a useful tool for body recomposition goals.

SR-9009 Side Effects

SR-9009: The Science, Benefits, and Insights into Its Usage

What is SR-9009?

How Does SR-9009 Work?

The Role of the Rev-ERB System

Circadian Rhythm Regulation: Influencing the body’s internal clock and aligning biological processes with day-night cycles.
Metabolic Regulation: Controlling the storage and breakdown of fat and glucose.
Inflammation Modulation: Suppressing pro-inflammatory pathways.

Benefits of SR-9009

1. Improved Sleep

2. Enhanced Energy and Endurance

3. Support for Metabolic Health

4. Reduction in Inflammation

Through the suppression of inflammatory pathways, SR-9009 may offer benefits for conditions linked to chronic inflammation, such as autoimmune disorders and metabolic syndromes.

5. Potential Aid in Fat Loss

By stimulating Rev-ERBα, SR-9009 enhances the breakdown of stored fats and reduces the generation of new fat cells. This makes it a useful tool for body recomposition goals. Due to it making the mitochondria more efficient and it improving sleep SR-9009 will help to burn fat through multiple different pathways.

6. Anti Tumor Effects

SR-9009 has also been shown to have certain anti tumor effects although this is still very early in the research.

7. Nootropic Effects

SR-9009 to me is a very powerful nootropic due to the alertness it helps to give me. SR-9009 is amazing for my overall productivity, and my cognitive function.

8. Cardio Protective

This compound has also been shown in early studies to be cardio protective.

Side Effects and Limitations

1. Insomnia

One of the most commonly reported side effects of SR-9009 is insomnia, particularly when taken late in the day. This is likely due to its impact on the circadian rhythm and energy regulation, making it crucial to dose earlier in the day to avoid disrupting sleep.

2. Lack of Research

Despite its promising benefits, SR-9009 is still in the research phase, with no approved human studies to date. Most findings are derived from animal studies or anecdotal reports, which limits its established safety profile.

3. Raised Liver Values

Some people who have used this have noticed elevated liver values. Although it is hard to say if what they were taking was actually SR-9009 or caused by something else.

Proper Route of Administration

The efficacy of SR-9009 depends heavily on the route of administration:

Injectable (Best): Injectable administration ensures high bioavailability, allowing SR-9009 to be effectively absorbed and utilized by the body.
Topical (Moderately Effective): Topical formulations provide a decent level of absorption but are less effective than injectable forms.
Oral (Practically Ineffective): Oral administration is considered almost useless due to extremely low bioavailability. SR-9009 is rapidly metabolized in the liver, leading to minimal active compound reaching systemic circulation.

SR-9009 vs Cardarine

While both SR-9009 and Cardarine (GW-501516) are popular for their metabolic and endurance-enhancing properties, they work through different mechanisms and are very different compounds.

Mechanism of Action: SR-9009 activates Rev-ERBα, while Cardarine activates PPARδ (peroxisome proliferator-activated receptor delta). Cardarine boosts endurance by enhancing fatty acid oxidation and glucose uptake in skeletal muscle, whereas SR-9009 improves overall mitochondrial function and energy expenditure.
Benefits: SR-9009 is more aligned with regulating the circadian rhythm, combating inflammation, and promoting mitochondrial health. Cardarine is more focused on enhancing athletic endurance and improving fat metabolism.
Side Effects: Cardarine has been linked to potential carcinogenic risks in animal studies, raising safety concerns. SR-9009 lacks this specific risk but suffers from limited research and lower bioavailability in oral forms.

My Experience with SR-9009

My experience was very interesting with SR-9009. Personal experience I always find to be very important when discussing these compounds. Now I really felt good on SR-9009. While from an endurance or fat loss standpoint things like Cardarine were a bit more effective. (Actually I think the fat loss was pretty similar as both alone are not the most powerful for fat loss).

From an energy, sleep, and mitochondrial perspective though SR-9009 was amazing, I will get more into my protocol. My energy felt awesome, my mood was perfect, and I noticed I was able to crank out more reps in the gym and my cardio got better.

I would use SR-9009 in the morning. When I would use it I would feel very awake. Awake in the way that you feel awake after a really good nights sleep. For me mornings can be hard as I get really groggy, but with SR-9009 I was very alert and ready to go.

SR-9009 Dosing

Dosing is as follows. I recommend pinning it everyday and likely twice per day if possible. Make sure though to keep the dosing as far away from bed time as possible. I would pin upon waking and then pin again about 6-7 hours later. I also always use it as an IM based shot.

My Protocol Was

Upon Waking: 30mg of SR-9009 Injected IM (around 8:00am)

Upon Waking from Midday Nap: Redose 10mg (around 2:00pm)

Now really you can go higer or lower by 5-10mg with this protocol. To me there is no point to push super high on the dosing though I found 30mg to be my sweet spot. I have also heard of dosing protocols from Leo that involve pinning it an hour before waking up then going back to sleep for a more natural wake up.

SR-9009 stacks really well with pretty much every fat burner.

Conclusion

SR-9009, or Stenabolic, represents an exciting advancement in metabolic and circadian rhythm research. By targeting the Rev-ERBα system, it offers a range of benefits, including improved energy, better sleep, enhanced endurance, and potential metabolic health improvements. However, its use is not without limitations, including the risk of insomnia and the lack of human research. Injectable administration remains the most effective route, with topical formulations as a secondary option.